SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB18755

Signal sequence   MRSAARRGRAAPAARDSLPVLLFLCLLLKTCEP

Length  33

Organism  Homo sapiens (Human)

UniProt ID  P51689,

Motif  1..33



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB18755.cif

Structure  SPKB18755.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3597.36244

Aliphatic index  109.6969697

Isoelectric point  11.25141841

Charge (pH=7)   3.875944884

Topological polar surface area  1438.96

Aromaticity  0.03030303

Average rotatable bonds  3.515151515

Number of hydrogen bond donors  54

Number of hydrogen bond acceptors  48

X logP energy  -12.83435

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.