General Information
SPKB ID SPKB18646
Signal sequence MKAFYGILIIFILISMIDLSKQ
Length 22
Organism Tityus serrulatus (Brazilian scorpion)
UniProt ID P46114,
Motif 1..22
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB18646.cif
Physicochemical Information
Molecular weight 2558.21884
Aliphatic index 164.0909091
Isoelectric point 9.256043355
Charge (pH=7) 0.996990302
Topological polar surface area 867.54
Aromaticity 0.136363636
Average rotatable bonds 4
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 32
X logP energy -0.432
Hydropathy 
Literature Information
Title Tityustoxin K alpha blocks voltage-gated noninactivating K+ channels and unblocks inactivating K+ channels blocked by alpha-dendrotoxin in synaptosomes.
Publication Year 1994
PubMed ID 7509073,
Patent ID NA,
