SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17927

Signal sequence   MRKQWLGICIAAGMLAA

Length  17

Organism  Escherichia coli (strain K12)

UniProt ID  P10100,

Motif  1..17



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  Sec/SPII



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17927.cif

Structure  SPKB17927.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1833.30134

Aliphatic index  115.2941176

Isoelectric point  9.833242293

Charge (pH=7)   1.935711238

Topological polar surface area  675.72

Aromaticity  0.058823529

Average rotatable bonds  3.588235294

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  24

X logP energy  -3.50033

Hydropathy 



Literature Information


Title  Genes encoding two lipoproteins in the leuS-dacA region of the Escherichia coli chromosome.

DOI  10.1128/jb.169.12.5692-5699.1987,

Publication Year  1987

PubMed ID  3316191,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.