SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17851

Signal sequence   MQIKHLITLFFLVLIVADQCSA

Length  22

Organism  Tityus stigmurus (Brazilian scorpion)

UniProt ID  P0DQT1,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17851.cif

Structure  SPKB17851.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2504.08694

Aliphatic index  159.5454545

Isoelectric point  7.359000943

Charge (pH=7)   0.027070125

Topological polar surface area  893.06

Aromaticity  0.090909091

Average rotatable bonds  3.772727273

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  32

X logP energy  -3.1045

Hydropathy 



Literature Information


Title  Structural characterization of a novel peptide with antimicrobial activity from the venom gland of the scorpion Tityus stigmurus: Stigmurin.

DOI  10.1016/j.peptides.2015.03.003,

Publication Year  2015

PubMed ID  25805002,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.