SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17728

Signal sequence   MKLSCGFLLILLVLSAMIATFSEVEAMKPS

Length  30

Organism  Tityus serrulatus (Brazilian scorpion)

UniProt ID  P0C174,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17728.cif

Structure  SPKB17728.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3244.02754

Aliphatic index  133.3333333

Isoelectric point  6.354537022

Charge (pH=7)   -0.061030239

Topological polar surface area  1126.22

Aromaticity  0.066666667

Average rotatable bonds  3.633333333

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  44

X logP energy  -5.6523

Hydropathy 



Literature Information


Title  Novel structural class of four disulfide-bridged peptides from Tityus serrulatus venom.

DOI  10.1016/s0006-291x(03)00082-2,

Publication Year  2003

PubMed ID  12589824,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.