SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17520

Signal sequence   MKFLLLFLVVLPIMGVFG

Length  18

Organism  Androctonus australis (Sahara scorpion)

UniProt ID  P01497,

Motif  1..18



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17520.cif

Structure  SPKB17520.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2037.67904

Aliphatic index  178.3333333

Isoelectric point  9.700002532

Charge (pH=7)   0.997689266

Topological polar surface area  575.25

Aromaticity  0.166666667

Average rotatable bonds  3.611111111

Number of hydrogen bond donors  19

Number of hydrogen bond acceptors  22

X logP energy  4.0168

Hydropathy 



Literature Information


Title  Neurotoxins active on insects: amino acid sequences, chemical modifications, and secondary structure estimation by circular dichroism of toxins from the scorpion Androctonus australis Hector.

DOI  10.1021/bi00458a021,

Publication Year  1990

PubMed ID  2334710,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.