SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17519

Signal sequence   MKANTMFIILCLSLSTLCVSS

Length  21

Organism  Aplysia californica (California sea hare)

UniProt ID  P01360,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17519.cif

Structure  SPKB17519.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2275.82334

Aliphatic index  130

Isoelectric point  8.229691165

Charge (pH=7)   0.873739834

Topological polar surface area  835.81

Aromaticity  0.047619048

Average rotatable bonds  3.619047619

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -7.6095

Hydropathy 



Literature Information


Title  Proteolytic processing of egg-laying hormone-related precursors in Aplysia. Identification of peptide regions critical for biological activity.

DOI  ,

Publication Year  1988

PubMed ID  3379066,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.