SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17507

Signal sequence   MRFPSIFTAVLFAASSALA

Length  19

Organism  Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)

UniProt ID  P01149,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  6KRL,

Predicted Structure ID  SPKB17507.cif

Structure  SPKB17507.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2000.38634

Aliphatic index  103.1578947

Isoelectric point  10.55000222

Charge (pH=7)   0.997980988

Topological polar surface area  721.15

Aromaticity  0.157894737

Average rotatable bonds  3.157894737

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  26

X logP energy  -5.37313

Hydropathy 



Literature Information


Title  Purification and amino acid sequence of mating factor from Saccharomyces cerevisiae.

DOI  10.1093/oxfordjournals.jbchem.a131864,

Publication Year  1977

PubMed ID  340452,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.