SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17409

Signal sequence   MKRMILFISCLLLIDIVVG

Length  19

Organism  Tityus serrulatus (Brazilian scorpion)

UniProt ID  O77463,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17409.cif

Structure  SPKB17409.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2177.83654

Aliphatic index  194.7368421

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  732.57

Aromaticity  0.052631579

Average rotatable bonds  3.947368421

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  27

X logP energy  -0.02513

Hydropathy 



Literature Information


Title  The complete amino acid sequence of toxin TsTX-VI isolated from the venom of the scorpion Tityus serrulatus.

DOI  10.1007/BF01025013,

Publication Year  1990

PubMed ID  2085384,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.