SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17395

Signal sequence   MSFLEEARAAGRAVVLALVLLLLPAVPVGA

Length  30

Organism  Homo sapiens (Human)

UniProt ID  O75095,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17395.cif

Structure  SPKB17395.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3047.73624

Aliphatic index  162.6666667

Isoelectric point  6.533466308

Charge (pH=7)   0.001527922

Topological polar surface area  1108.27

Aromaticity  0.033333333

Average rotatable bonds  3.2

Number of hydrogen bond donors  38

Number of hydrogen bond acceptors  37

X logP energy  -5.28106

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.