SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB17010

Signal sequence   MNECVNKLLHLKFLFYFILGIQ

Length  22

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  G5CKU5,

Motif  1..22



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB17010.cif

Structure  SPKB17010.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2684.29584

Aliphatic index  137.2727273

Isoelectric point  8.526281002

Charge (pH=7)   1.027253315

Topological polar surface area  941.94

Aromaticity  0.181818182

Average rotatable bonds  4.090909091

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  33

X logP energy  -1.3466

Hydropathy 



Literature Information


Title  Identification of the novel bioactive peptides dRYamide-1 and dRYamide-2, ligands for a neuropeptide Y-like receptor in Drosophila.

DOI  10.1016/j.bbrc.2011.06.081,

Publication Year  2011

PubMed ID  21704020,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.