General Information
SPKB ID SPKB16962
Signal sequence MTSIPVSSFLLAALVLQYATSDA
Length 23
Organism Tabanus yao (Horsefly)
UniProt ID F8QQG5,
Motif 1..23
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB16962.cif
Physicochemical Information
Molecular weight 2398.79684
Aliphatic index 127.3913043
Isoelectric point 3.749986963
Charge (pH=7) -1.002419631
Topological polar surface area 916.73
Aromaticity 0.086956522
Average rotatable bonds 3.217391304
Number of hydrogen bond donors 32
Number of hydrogen bond acceptors 34
X logP energy -8.3927
Hydropathy 
Literature Information
Title A novel family of RGD-containing disintegrins (Tablysin-15) from the salivary gland of the horsefly Tabanus yao targets αIIbβ3 or αVβ3 and inhibits platelet aggregation and angiogenesis.
DOI 10.1160/TH11-01-0029,
Publication Year 2011
PubMed ID 21475772,
Patent ID NA,
