SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB16671

Signal sequence   MNYLLVLTLASLLALGVNG

Length  19

Organism  Parabuthus granulatus (Granulated thick-tailed scorpion) (Androctonus granulatus)

UniProt ID  B7SNV8,

Motif  1..19



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB16671.cif

Structure  SPKB16671.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  1975.41714

Aliphatic index  184.7368421

Isoelectric point  6.093198033

Charge (pH=7)   -0.002866115

Topological polar surface area  733.99

Aromaticity  0.052631579

Average rotatable bonds  3.368421053

Number of hydrogen bond donors  25

Number of hydrogen bond acceptors  26

X logP energy  -4.1127

Hydropathy 



Literature Information


Title  Heterologous expression of a gene that codes for Pg8, a scorpion toxin of Parabuthus granulatus, capable of generating protecting antibodies in mice.

DOI  10.1016/j.toxicon.2009.02.011,

Publication Year  2009

PubMed ID  19233226,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.