SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB16462

Signal sequence   MLFRARGPVRGRGWGRPAEAPRRGRSPPWSPAWICCWALAGCQAAWA

Length  47

Organism  Homo sapiens (Human)

UniProt ID  A8MWY0,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB16462.cif

Structure  SPKB16462.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5221.10104

Aliphatic index  50.21276596

Isoelectric point  12.27831557

Charge (pH=7)   6.813808784

Topological polar surface area  2044.18

Aromaticity  0.127659574

Average rotatable bonds  3.234042553

Number of hydrogen bond donors  78

Number of hydrogen bond acceptors  64

X logP energy  -17.87564

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.