SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB16242

Signal sequence   MTAFKRVLIAMISALLAGTTGMFVSAGAAHA

Length  31

Organism  Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)

UniProt ID  A0QPU4,

Motif  1..31



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB16242.cif

Structure  SPKB16242.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3108.76894

Aliphatic index  107.4193548

Isoelectric point  11.65178972

Charge (pH=7)   2.088595045

Topological polar surface area  1154.07

Aromaticity  0.064516129

Average rotatable bonds  3.258064516

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  43

X logP energy  -10.23203

Hydropathy 



Literature Information


Title  MspA provides the main hydrophilic pathway through the cell wall of Mycobacterium smegmatis.

DOI  10.1046/j.1365-2958.2001.02394.x,

Publication Year  2001

PubMed ID  11309127,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.