SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15897

Signal sequence   MKFLIFAFFGGVHLLSLCSG

Length  20

Organism  Homo sapiens (Human)

UniProt ID  Q9Y646,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB15897.cif

Structure  SPKB15897.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2187.68874

Aliphatic index  117

Isoelectric point  8.552755748

Charge (pH=7)   1.026623641

Topological polar surface area  711.38

Aromaticity  0.2

Average rotatable bonds  3.5

Number of hydrogen bond donors  26

Number of hydrogen bond acceptors  27

X logP energy  -1.8568

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.