SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15880

Signal sequence   MACRWSTKESPRWRSALLLLFLAGVYGNGALA

Length  32

Organism  Homo sapiens (Human)

UniProt ID  Q9Y561,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB15880.cif

Structure  SPKB15880.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3539.17664

Aliphatic index  97.8125

Isoelectric point  10.44865809

Charge (pH=7)   2.936629324

Topological polar surface area  1381.47

Aromaticity  0.125

Average rotatable bonds  3.5

Number of hydrogen bond donors  52

Number of hydrogen bond acceptors  46

X logP energy  -10.80179

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.