SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15879

Signal sequence   MADKVRRQRPRRRVCWALVAVLLADLLALSDT

Length  32

Organism  Homo sapiens (Human)

UniProt ID  Q9Y4L1,

Motif  1..32



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB15879.cif

Structure  SPKB15879.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3693.43624

Aliphatic index  125

Isoelectric point  11.84341824

Charge (pH=7)   3.937034134

Topological polar surface area  1565.29

Aromaticity  0.03125

Average rotatable bonds  3.84375

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  48

X logP energy  -12.88838

Hydropathy 



Literature Information


Title  N-terminome analysis of the human mitochondrial proteome.

DOI  10.1002/pmic.201400617,

Publication Year  2015

PubMed ID  25944712,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.