SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15752

Signal sequence   MTKSIKRPPPFSCKQVLLTYVILAYTVAA

Length  29

Organism  Drosophila melanogaster (Fruit fly)

UniProt ID  Q9VZX1,

Motif  1..29



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB15752.cif

Structure  SPKB15752.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3239.96874

Aliphatic index  107.5862069

Isoelectric point  10.33327911

Charge (pH=7)   3.933420342

Topological polar surface area  1176.41

Aromaticity  0.103448276

Average rotatable bonds  3.482758621

Number of hydrogen bond donors  42

Number of hydrogen bond acceptors  44

X logP energy  -7.38553

Hydropathy 



Literature Information


Title  Toll-6 and Toll-7 function as neurotrophin receptors in the Drosophila melanogaster CNS.

DOI  10.1038/nn.3474,

Publication Year  2013

PubMed ID  23892553,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.