SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15333

Signal sequence   MKLLSLVAVVGCLLVPPAEA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  Q9P0T7,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  9DNX,

Predicted Structure ID  SPKB15333.cif

Structure  SPKB15333.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2023.56354

Aliphatic index  170.5

Isoelectric point  6.231833229

Charge (pH=7)   -0.062510328

Topological polar surface area  682.19

Aromaticity  0

Average rotatable bonds  3.15

Number of hydrogen bond donors  23

Number of hydrogen bond acceptors  26

X logP energy  -2.1635

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.