SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15139

Signal sequence   MITTSLRRRTAAAVLSLSAVLATTAATAPGAAPAPSAAPAKA

Length  42

Organism  Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)

UniProt ID  Q9L1E4,

Motif  1..42



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB15139.cif

Structure  SPKB15139.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3976.65074

Aliphatic index  95.95238095

Isoelectric point  12.80742779

Charge (pH=7)   3.997679332

Topological polar surface area  1635.28

Aromaticity  0

Average rotatable bonds  2.857142857

Number of hydrogen bond donors  59

Number of hydrogen bond acceptors  58

X logP energy  -22.30179

Hydropathy 



Literature Information


Title  ADP-ribosylation of guanosine by SCO5461 protein secreted from Streptomyces coelicolor.

DOI  10.1016/j.toxicon.2012.11.019,

Publication Year  2013

PubMed ID  23212047,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.