SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB15025

Signal sequence   MKLLWQVTVHHHTWNAILLPFVYLTAQVWILCAAIAAA

Length  38

Organism  Homo sapiens (Human)

UniProt ID  Q9HBW1,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  3ZYI,

Predicted Structure ID  SPKB15025.cif

Structure  SPKB15025.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4344.25004

Aliphatic index  141.3157895

Isoelectric point  8.544937489

Charge (pH=7)   1.207591408

Topological polar surface area  1500.85

Aromaticity  0.131578947

Average rotatable bonds  3.447368421

Number of hydrogen bond donors  53

Number of hydrogen bond acceptors  52

X logP energy  -3.3586

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.