SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14959

Signal sequence   MKRLFVITAFFLFGAEAQNSVIDA

Length  24

Organism  Holotrichia diomphalia (Korean black chafer)

UniProt ID  Q9GRW0,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14959.cif

Structure  SPKB14959.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2689.16764

Aliphatic index  105.8333333

Isoelectric point  6.494323083

Charge (pH=7)   -0.0000924

Topological polar surface area  1021.78

Aromaticity  0.166666667

Average rotatable bonds  3.666666667

Number of hydrogen bond donors  35

Number of hydrogen bond acceptors  34

X logP energy  -6.27423

Hydropathy 



Literature Information


Title  A masquerade-like serine proteinase homologue is necessary for phenoloxidase activity in the coleopteran insect, Holotrichia diomphalia larvae.

DOI  10.1046/j.1432-1327.2000.01695.x,

Publication Year  2000

PubMed ID  11012672,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.