General Information
SPKB ID SPKB14597
Signal sequence MERPWGAADGLSRWPHGLGLLLLLQLLPPSTLS
Length 33
Organism Homo sapiens (Human)
UniProt ID Q99523,
Motif 1..33
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location Lysosome
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID 6X3L,
Predicted Structure ID SPKB14597.cif
Physicochemical Information
Molecular weight 3596.25084
Aliphatic index 124.2424242
Isoelectric point 7.551922216
Charge (pH=7) 0.091108375
Topological polar surface area 1342.03
Aromaticity 0.060606061
Average rotatable bonds 3.333333333
Number of hydrogen bond donors 46
Number of hydrogen bond acceptors 45
X logP energy -8.38076
Hydropathy 
Literature Information
