SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14501

Signal sequence   MQPPRERLVVTGRAGWMGMGRGAGRSALGFWPTLAFLLCSFPAATSP

Length  47

Organism  Homo sapiens (Human)

UniProt ID  Q96B86,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14501.cif

Structure  SPKB14501.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5006.90344

Aliphatic index  66.59574468

Isoelectric point  12.32403132

Charge (pH=7)   3.93776815

Topological polar surface area  1900.82

Aromaticity  0.106382979

Average rotatable bonds  3.234042553

Number of hydrogen bond donors  69

Number of hydrogen bond acceptors  65

X logP energy  -17.75705

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.