SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14409

Signal sequence   MGPLINRCKKILLPTTVPPATMRIWLLGGLLPFLLLLSGLQRPTEG

Length  46

Organism  Homo sapiens (Human)

UniProt ID  Q93070,

Motif  1..46



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14409.cif

Structure  SPKB14409.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  5040.25044

Aliphatic index  135.6521739

Isoelectric point  11.55108258

Charge (pH=7)   3.937184705

Topological polar surface area  1798.24

Aromaticity  0.043478261

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  62

Number of hydrogen bond acceptors  63

X logP energy  -9.25239

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.