SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14219

Signal sequence   MRVLCAFPEAMPSSNSRPPACLAPGALYLALLLHLSLSSQA

Length  41

Organism  Homo sapiens (Human)

UniProt ID  Q8WWQ2,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14219.cif

Structure  SPKB14219.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4298.12014

Aliphatic index  109.7560976

Isoelectric point  8.234455687

Charge (pH=7)   0.965862044

Topological polar surface area  1600.94

Aromaticity  0.048780488

Average rotatable bonds  3.195121951

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  59

X logP energy  -14.82846

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.