SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14133

Signal sequence   MPLKHYLLLLVGCQAWGAGLA

Length  21

Organism  Homo sapiens (Human)

UniProt ID  Q8TF66,

Motif  1..21



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14133.cif

Structure  SPKB14133.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2254.77954

Aliphatic index  139.5238095

Isoelectric point  8.530526343

Charge (pH=7)   1.025773226

Topological polar surface area  770.34

Aromaticity  0.095238095

Average rotatable bonds  3.333333333

Number of hydrogen bond donors  27

Number of hydrogen bond acceptors  28

X logP energy  -1.7975

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.