SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14128

Signal sequence   MECALLLACAFPAAGSGPPRGLAGLGRVAKALQLCCLCCASVAAALA

Length  47

Organism  Homo sapiens (Human)

UniProt ID  Q8TE60,

Motif  1..47



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14128.cif

Structure  SPKB14128.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4504.50274

Aliphatic index  114.6808511

Isoelectric point  8.115111907

Charge (pH=7)   1.62760947

Topological polar surface area  1646.22

Aromaticity  0.021276596

Average rotatable bonds  3

Number of hydrogen bond donors  62

Number of hydrogen bond acceptors  62

X logP energy  -16.29466

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.