SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14127

Signal sequence   MGKNREMRLTHICCCCLLYQLGFLSNG

Length  27

Organism  Homo sapiens (Human)

UniProt ID  Q8TE59,

Motif  1..27



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14127.cif

Structure  SPKB14127.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3104.74764

Aliphatic index  86.66666667

Isoelectric point  8.341166136

Charge (pH=7)   1.841617579

Topological polar surface area  1225.68

Aromaticity  0.074074074

Average rotatable bonds  3.888888889

Number of hydrogen bond donors  47

Number of hydrogen bond acceptors  45

X logP energy  -11.53416

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.