SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14006

Signal sequence   MLRPQGLLWLPLLFTSVCVMLNSNVLLWITALAIKFTLIDSQA

Length  43

Organism  Homo sapiens (Human)

UniProt ID  Q8NFZ3,

Motif  1..43



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14006.cif

Structure  SPKB14006.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4844.93904

Aliphatic index  154.1860465

Isoelectric point  8.545113874

Charge (pH=7)   0.936157722

Topological polar surface area  1718.48

Aromaticity  0.093023256

Average rotatable bonds  3.604651163

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  60

X logP energy  -7.28573

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.