SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14005

Signal sequence   MRVFLLCAYILLLMVSQLRA

Length  20

Organism  Homo sapiens (Human)

UniProt ID  Q8NFY4,

Motif  1..20



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14005.cif

Structure  SPKB14005.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2354.01434

Aliphatic index  175.5

Isoelectric point  9.49995979

Charge (pH=7)   1.935152547

Topological polar surface area  823.57

Aromaticity  0.1

Average rotatable bonds  3.9

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  29

X logP energy  -1.30466

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.