SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB14000

Signal sequence   MALRGTLRPLKVRRRREMLPQQVGFVCAVLALVCCASG

Length  38

Organism  Homo sapiens (Human)

UniProt ID  Q8NFF2,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB14000.cif

Structure  SPKB14000.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4200.17644

Aliphatic index  110.2631579

Isoelectric point  11.84382564

Charge (pH=7)   5.813520373

Topological polar surface area  1683.8

Aromaticity  0.026315789

Average rotatable bonds  3.684210526

Number of hydrogen bond donors  64

Number of hydrogen bond acceptors  56

X logP energy  -15.10548

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.