SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13985

Signal sequence   MLWFSGVGALAERYCRRSPGITCCVLLLLNCSGVPMSLA

Length  39

Organism  Homo sapiens (Human)

UniProt ID  Q8N8U9,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13985.cif

Structure  SPKB13985.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4189.07154

Aliphatic index  110

Isoelectric point  8.337291597

Charge (pH=7)   1.75100021

Topological polar surface area  1554.8

Aromaticity  0.076923077

Average rotatable bonds  3.384615385

Number of hydrogen bond donors  60

Number of hydrogen bond acceptors  57

X logP energy  -13.22439

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.