SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13976

Signal sequence   MKCLGKRRGQAAAFLPLCWLFLKILQPGHS

Length  30

Organism  Homo sapiens (Human)

UniProt ID  Q8N4T0,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13976.cif

Structure  SPKB13976.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3384.17114

Aliphatic index  101

Isoelectric point  11.06162096

Charge (pH=7)   4.964052234

Topological polar surface area  1242.38

Aromaticity  0.1

Average rotatable bonds  3.7

Number of hydrogen bond donors  45

Number of hydrogen bond acceptors  43

X logP energy  -7.02876

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.