General Information
SPKB ID SPKB13956
Signal sequence MRTFLFLFAVLFFLTPAKNA
Length 20
Organism Homo sapiens (Human)
UniProt ID Q8N104,
Motif 1..20
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB13956.cif
Physicochemical Information
Molecular weight 2347.88974
Aliphatic index 107.5
Isoelectric point 11.65177567
Charge (pH=7) 1.997685954
Topological polar surface area 778.9
Aromaticity 0.25
Average rotatable bonds 3.6
Number of hydrogen bond donors 27
Number of hydrogen bond acceptors 27
X logP energy -0.98833
Hydropathy 
Literature Information
Title Structural basis for the interaction of human β-defensin 6 and its putative chemokine receptor CCR2 and breast cancer microvesicles.
DOI 10.1016/j.jmb.2013.08.001,
Publication Year 2013
PubMed ID 23938203,
Patent ID NA,
