General Information
SPKB ID SPKB13859
Signal sequence MRISQICTVLSTVTSAVA
Length 18
Organism Aspergillus oryzae (Yellow koji mold)
UniProt ID Q8J2T0,
Motif 1..18
Activity Information
Pathway SRP-dependent
Natural/Artificial Natural
Subcellular location ER
Secretion efficiency NA
Type Sec/SPI
Structure Information
PDB ID NA,
Predicted Structure ID SPKB13859.cif
Physicochemical Information
Molecular weight 1880.24834
Aliphatic index 124.4444444
Isoelectric point 8.549912035
Charge (pH=7) 0.936006272
Topological polar surface area 784.39
Aromaticity 0
Average rotatable bonds 3.388888889
Number of hydrogen bond donors 30
Number of hydrogen bond acceptors 29
X logP energy -9.88303
Hydropathy
Literature Information
Title Large propeptides of fungal beta-N-acetylhexosaminidases are novel enzyme regulators that must be intracellularly processed to control activity, dimerization, and secretion into the extracellular environment.
DOI 10.1021/bi061828m,
Publication Year 2007
PubMed ID 17302431,
Patent ID NA,