SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13840

Signal sequence   MGAAAAEAPLRLPAAPPLAFCCYTSVLLLFAFSLPGSRA

Length  39

Organism  Homo sapiens (Human)

UniProt ID  Q8IYR6,

Motif  1..39



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13840.cif

Structure  SPKB13840.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3965.74514

Aliphatic index  103.0769231

Isoelectric point  8.222843715

Charge (pH=7)   0.874952953

Topological polar surface area  1387.42

Aromaticity  0.102564103

Average rotatable bonds  2.948717949

Number of hydrogen bond donors  49

Number of hydrogen bond acceptors  51

X logP energy  -10.16966

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.