SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13582

Signal sequence   MEPGPTAAQRRCSLPPWLPLGLLLWSGLALG

Length  31

Organism  Homo sapiens (Human)

UniProt ID  Q86WC4,

Motif  1..31



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  7BXU,

Predicted Structure ID  SPKB13582.cif

Structure  SPKB13582.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3301.95844

Aliphatic index  110.3225806

Isoelectric point  8.549845238

Charge (pH=7)   0.937778084

Topological polar surface area  1188.83

Aromaticity  0.064516129

Average rotatable bonds  3.129032258

Number of hydrogen bond donors  41

Number of hydrogen bond acceptors  41

X logP energy  -7.41946

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.