SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13567

Signal sequence   MMFRSDRMWSCHWKWKPSPLLFLFALYIMCVPHSVWG

Length  37

Organism  Homo sapiens (Human)

UniProt ID  Q86SQ4,

Motif  1..37



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13567.cif

Structure  SPKB13567.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4588.57164

Aliphatic index  71.08108108

Isoelectric point  9.497848946

Charge (pH=7)   3.054852429

Topological polar surface area  1519.36

Aromaticity  0.216216216

Average rotatable bonds  3.72972973

Number of hydrogen bond donors  57

Number of hydrogen bond acceptors  56

X logP energy  -2.83206

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.