SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13256

Signal sequence   MDLAPDRATGRPWLPLHTLSVSQLLRVFWLLSLLPGQA

Length  38

Organism  Homo sapiens (Human)

UniProt ID  Q6V0I7,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8EGW,

Predicted Structure ID  SPKB13256.cif

Structure  SPKB13256.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4270.06404

Aliphatic index  125.7894737

Isoelectric point  10.31041092

Charge (pH=7)   1.089776425

Topological polar surface area  1612.75

Aromaticity  0.078947368

Average rotatable bonds  3.447368421

Number of hydrogen bond donors  56

Number of hydrogen bond acceptors  53

X logP energy  -10.12549

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.