SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13254

Signal sequence   MENWTGRPWLYLLLLLSLPQLCLD

Length  24

Organism  Homo sapiens (Human)

UniProt ID  Q6UY14,

Motif  1..24



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13254.cif

Structure  SPKB13254.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2888.47834

Aliphatic index  146.25

Isoelectric point  4.184373867

Charge (pH=7)   -1.062622535

Topological polar surface area  1029.99

Aromaticity  0.125

Average rotatable bonds  3.708333333

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  35

X logP energy  -2.19663

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.