SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13241

Signal sequence   MAEPGHSHHLSARVRGRTERRIPRLWRLLLWAGTAFQVTQG

Length  41

Organism  Homo sapiens (Human)

UniProt ID  Q6UXG2,

Motif  1..41



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13241.cif

Structure  SPKB13241.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  4749.48854

Aliphatic index  80.97560976

Isoelectric point  12.62496323

Charge (pH=7)   5.274238639

Topological polar surface area  2022.59

Aromaticity  0.073170732

Average rotatable bonds  3.731707317

Number of hydrogen bond donors  75

Number of hydrogen bond acceptors  62

X logP energy  -19.43181

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.