SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13232

Signal sequence   MARPGMERWRDRLALVTGASGGIGAAVARA

Length  30

Organism  Homo sapiens (Human)

UniProt ID  Q6UWP2,

Motif  1..30



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  1XG5,

Predicted Structure ID  SPKB13232.cif

Structure  SPKB13232.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3097.60974

Aliphatic index  81.66666667

Isoelectric point  12.32397707

Charge (pH=7)   3.00018935

Topological polar surface area  1338.78

Aromaticity  0.033333333

Average rotatable bonds  3.366666667

Number of hydrogen bond donors  50

Number of hydrogen bond acceptors  42

X logP energy  -15.03055

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.