SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13182

Signal sequence   MGTRGAVMPPPMWGLLGCCFVCAWA

Length  25

Organism  Homo sapiens (Human)

UniProt ID  Q6PRD1,

Motif  1..25



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  8D1B,

Predicted Structure ID  SPKB13182.cif

Structure  SPKB13182.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2655.28314

Aliphatic index  66.4

Isoelectric point  8.04679067

Charge (pH=7)   0.81205684

Topological polar surface area  849.06

Aromaticity  0.12

Average rotatable bonds  3

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -4.07493

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.