SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13157

Signal sequence   MTRGGPGGRPGLPQPPPLLLLLLLLPLLLVTAEPPKPA

Length  38

Organism  Homo sapiens (Human)

UniProt ID  Q6P4A8,

Motif  1..38



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  Lysosome

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13157.cif

Structure  SPKB13157.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3904.84284

Aliphatic index  136.0526316

Isoelectric point  11.47969967

Charge (pH=7)   1.999457766

Topological polar surface area  1322.79

Aromaticity  0

Average rotatable bonds  2.973684211

Number of hydrogen bond donors  40

Number of hydrogen bond acceptors  47

X logP energy  -5.89556

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.