SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13112

Signal sequence   MTIKRFFVCAGIMGCLSLNPAMA

Length  23

Organism  Escherichia coli

UniProt ID  Q6EZC3,

Motif  1..23



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB13112.cif

Structure  SPKB13112.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2475.09964

Aliphatic index  93.47826087

Isoelectric point  8.828181491

Charge (pH=7)   1.873736522

Topological polar surface area  866.2

Aromaticity  0.086956522

Average rotatable bonds  3.47826087

Number of hydrogen bond donors  32

Number of hydrogen bond acceptors  34

X logP energy  -6.02193

Hydropathy 



Literature Information


Title  A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli.

DOI  10.1084/jem.20040392,

Publication Year  2004

PubMed ID  15226357,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.