SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB13111

Signal sequence   MLKILWTYILFLLFISASARA

Length  21

Organism  Escherichia coli

UniProt ID  Q6EZC2,

Motif  1..21



Activity Information


Pathway  NA

Natural/Artificial  Natural

Subcellular location  Cell membrane

Secretion efficiency  NA

Type  NA



Structure Information


PDB ID  2IY9,

Predicted Structure ID  SPKB13111.cif

Structure  SPKB13111.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2471.08494

Aliphatic index  162.8571429

Isoelectric point  10.45492462

Charge (pH=7)   1.99683554

Topological polar surface area  829.95

Aromaticity  0.19047619

Average rotatable bonds  3.761904762

Number of hydrogen bond donors  31

Number of hydrogen bond acceptors  29

X logP energy  0.19127

Hydropathy 



Literature Information


Title  A new family of potent AB(5) cytotoxins produced by Shiga toxigenic Escherichia coli.

DOI  10.1084/jem.20040392,

Publication Year  2004

PubMed ID  15226357,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.