SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12959

Signal sequence   MEASSPLDPVGRLVAFCRGGVHLAVLLLFLSPSTL

Length  35

Organism  Rattus norvegicus (Rat)

UniProt ID  Q63135,

Motif  1..35



Activity Information


Pathway  SRP-dependent

Natural/Artificial  Natural

Subcellular location  ER

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  2XRB,

Predicted Structure ID  SPKB12959.cif

Structure  SPKB12959.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  3667.38574

Aliphatic index  130.8571429

Isoelectric point  7.360757205

Charge (pH=7)   0.029133659

Topological polar surface area  1354.58

Aromaticity  0.057142857

Average rotatable bonds  3.257142857

Number of hydrogen bond donors  48

Number of hydrogen bond acceptors  48

X logP energy  -10.30306

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.