SPKB

Signal Peptide Knowledge Base

General Information


SPKB ID  SPKB12778

Signal sequence   MNKKKLGIRLLSLLALGGFVLANPVFA

Length  27

Organism  Streptococcus pyogenes serotype M6 (strain ATCC BAA-946 / MGAS10394)

UniProt ID  Q5X9P3,

Motif  1..27



Activity Information


Pathway  Sec

Natural/Artificial  Natural

Subcellular location  Extracellular environment

Secretion efficiency  NA

Type  Sec/SPI



Structure Information


PDB ID  NA,

Predicted Structure ID  SPKB12778.cif

Structure  SPKB12778.cif
Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)
Loading PAE…
Expected Position Error (Ångströms)


Physicochemical Information


Molecular weight  2884.60584

Aliphatic index  148.1481481

Isoelectric point  11.92450937

Charge (pH=7)   3.997095887

Topological polar surface area  1057.5

Aromaticity  0.074074074

Average rotatable bonds  3.62962963

Number of hydrogen bond donors  36

Number of hydrogen bond acceptors  36

X logP energy  -5.22413

Hydropathy 



Literature Information


Title  NA

DOI  NA,

Publication Year  0

PubMed ID  NA,

Patent ID  NA,



Faculty of Applied Sciences, Macao Polytechnic University, Macao, China.